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Article

Specific and sustained down-regulation of genes involved in fatty acid metabolism is not a hallmark of progression to cardiac failure in mice.

Journal of molecular and cellular cardiology - 1 Jun 2006

de Brouwer K F J, Degens H, Aartsen W M, Lindhout M, Bitsch N J J E, Gilde A J, Willemsen P H M, Janssen B J A, van der Vusse G J, van Bilsen M

Abstract excerpt

Preferential and specific down-regulation of genes involved in fatty acid (FA) uptake and metabolism is considered a hallmark of severe hypertrophic remodeling and progression to cardiac failure. Therefore, we investigated the time course of changes in cardiac metabolic gene expression (1) in mice subjected to regional myocardial infarction (MI) for 4 days, 1 month, or 3 months and (2) in mice overexpressing...

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Identifiers

PMID: 16697005
DOI: 10.1016/j.yjmcc.2006.03.429

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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