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Article

High-resolution mutation mapping reveals parallel experimental evolution in yeast.

PLoS biology - 1 Jul 2006

Segrè Ayellet V, Murray Andrew W, Leu Jun-Yi

Abstract excerpt

Understanding the genetic basis of evolutionary adaptation is limited by our ability to efficiently identify the genomic locations of adaptive mutations. Here we describe a method that can quickly and precisely map the genetic basis of naturally and experimentally evolved complex traits using linkage analysis. A yeast strain that expresses the evolved trait is crossed to a distinct strain background and DNA from...

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Identifiers

PMID: 16856782
DOI: 10.1371/journal.pbio.0040256
PMCID: PMC1514788

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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