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Article

Sequence variants of the CRH 5'-flanking region: effects on DNA-protein interactions studied by EMSA in PC12 cells.

Annals of the New York Academy of Sciences - 1 Jun 2006

Wagner Uta, Wahle Matthias, Malysheva Olga, Wagner Ulf, Häntzschel Holm, Baerwald Christoph

Abstract excerpt

Recently, studies in adult rheumatoid arthritis patients have shown an association with four single-nucleotide polymorphisms (SNPs) in the 3.7-kb regulatory region of human corticotropin-releasing hormone (hCRH) gene located at positions -3531, -3371, -2353, and -684 bp. Three of these novel polymorphisms are in absolute linkage disequilibrium, resulting in three combined alleles, named A1B1, A2B1, and A2B2. To...

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Share to 5' Flanking Region
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electrophoretic Mobility Shift Assay

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Share to Promoter Regions, Genetic

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Source

Identifiers

PMID: 16855132
DOI: 10.1196/annals.1351.003

Genes

CRH
ATF6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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