Article
C/EBP activates the human corticotropin-releasing hormone gene promoter.
Molecular and cellular endocrinology - 31 Oct 1997
Stephanou A, Okosi A, Knight R A, Chowdrey H S, Latchman D S
Abstract excerpt
The purpose of these studies was to identify whether transcription factors, associated with cytokine signalling, affected promoter activity of the corticotropin releasing hormone (CRH) gene. Fragments of a 3.6 kb sequence of the human CRH gene promoter were amplified by PCR and ligated upstream of a CAT reporter. These constructs were transfected into a variety of cell lines, either alone or together, with...
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