Article
Characterization of a human-specific regulator of placental corticotropin-releasing hormone.
Molecular endocrinology (Baltimore, Md.) - 1 Aug 1998
Scatena C D, Adler S
Abstract excerpt
The hypothalamic hormone CRH is also expressed in the placentas of humans and higher primates and may play an important role in the regulation of labor. In choriocarcinoma cell lines, activation of cAMP-dependent pathways increases human (h)CRH reporter gene expression. A cAMP-responsive region d...
Topics
- Activating Transcription Factor 2
- Base Sequence
- Binding Sites
- Corticotropin-Releasing Hormone
- Cyclic AMP
- Cyclic AMP Response Element-Binding Protein
- DNA Methylation
- DNA-Binding Proteins
- Female
- HeLa Cells
- Humans
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Placenta
- Pregnancy
- Promoter Regions, Genetic
- Regulatory Sequences, Nucleic Acid