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Article

Characterization of a human-specific regulator of placental corticotropin-releasing hormone.

Molecular endocrinology (Baltimore, Md.) - 1 Aug 1998

Scatena C D, Adler S

Abstract excerpt

The hypothalamic hormone CRH is also expressed in the placentas of humans and higher primates and may play an important role in the regulation of labor. In choriocarcinoma cell lines, activation of cAMP-dependent pathways increases human (h)CRH reporter gene expression. A cAMP-responsive region distinct from the cAMP response element at -220 bp, has been identified between -200 and -99 bp, and a candidate...

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Source

Identifiers

PMID: 9717848
DOI: 10.1210/mend.12.8.0150

Genes

CRH
ATF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Characterization of a human-specific regulator of placental corticotropin-releasing hormone.PMID 9717848Read ↗

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Stimulus-Induced Activation of the Glycoprotein Hormone α-Subunit Promoter in Human Placental Choriocarcinoma Cells: Major role of a Tandem cAMP Response ElementSemantic proximity Read ↗

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Novel Cyclic Adenosine 3′,5′- Monophosphate Response Element in the Human Chorionic Gonadotropin β-Subunit GeneSemantic proximity Read ↗

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