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Article

Distribution of corticotropin-releasing hormone promoter polymorphism in different ethnic groups: evidence for natural selection in human populations.

Immunogenetics - 1 Sept 1999

Baerwald C G, Mok C C, Fife M S, Tikly M, Lau C S, Wordsworth B P, Ollier B, Panayi G S, Lanchbury J S

Abstract excerpt

The regulatory region of the corticotropin-releasing hormone (CRH) is highly conserved across species and plays a crucial role in the response of the organism to stress. Release of CRH initiates a cascade of events leading to the release of cortisol and the regulation of inflammatory and immune events. In this report we describe polymorphisms in the 5' regulatory region of the CRH gene in humans. We studied the...

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Source

Identifiers

PMID: 10436184
DOI: 10.1007/s002510050570

Genes

CRH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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