Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Promoter polymorphisms regulating corticotrophin-releasing hormone transcription in vitro.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme - 1 Feb 2006

Wagner U, Wahle M, Moritz F, Wagner U, Häntzschel H, Baerwald C G O

Abstract excerpt

To investigate whether polymorphisms in the corticotrophin-releasing hormone (CRH) promoter are associated with altered CRH gene regulation, we studied the reactivity of three recently described promoter variants in vitro. The 3625 bp variants A1B1, A2B1 and A2B2 of the human CRH promoter were cloned in the 5' region to a luciferase reporter gene and transiently transfected into both mouse anterior pituitary...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 8-Bromo Cyclic Adenosine Monophosphate
Share to Activating Transcription Factor 6

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Corticotropin-Releasing Hormone

Share to Cytokines

Share to PC12 Cells

Share to Transcription, Genetic

Share to Transfection

Source

Identifiers

PMID: 16523405
DOI: 10.1055/s-2006-925115

Genes

CRH
ATF6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Promoter polymorphisms regulating corticotrophin-releasing hormone transcription in vitro.PMID 16523405Read ↗

Sequence variants of the CRH 5'-flanking region: effects on DNA-protein interactions studied by EMSA in PC12 cells.Semantic proximity Read ↗

C/EBP activates the human corticotropin-releasing hormone gene promoter.Semantic proximity Read ↗

Characterization of a human-specific regulator of placental corticotropin-releasing hormone.Semantic proximity Read ↗

Single nucleotide polymorphisms in the human corticosteroid-binding globulin promoter alter transcriptional activity.Semantic proximity Read ↗

Distribution of corticotropin-releasing hormone promoter polymorphism in different ethnic groups: evidence for natural selection in human populations.Semantic proximity Read ↗

Estrogen receptor (ER)-mediated transcriptional regulation of the human corticotropin-releasing hormone-binding protein promoter: differential effects of ERalpha and ERbeta.Semantic proximity Read ↗

The human MC2-R gene expression: different aspects of its control.Semantic proximity Read ↗

Corticotropin releasing hormone promoter polymorphisms in giant cell arteritis and polymyalgia rheumatica.Semantic proximity Read ↗

Interplay of pituitary adenylate cyclase-activating polypeptide with a silencer element to regulate the upstream promoter of the human gonadotropin-releasing hormone receptor gene.Semantic proximity Read ↗

Regulation of Corticotropin-Releasing Hormone Type 2 Receptors by Multiple Promoters and Alternative Splicing: Identification of Multiple Splice VariantsSemantic proximity Read ↗

Corticotropin releasing hormone (CRH) promoter polymorphisms in various ethnic groups of patients with rheumatoid arthritis.Semantic proximity Read ↗

Common genetic variants in the chromogranin A promoter alter autonomic activity and blood pressure.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.