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Article

Identification of alternative amino acid substitutions in drug-resistant variants of the HIV-1 reverse transcriptase.

AIDS (London, England) - 13 Jul 2006

Berkhout Ben, Back Nicole Kt, de Ronde Anthony, Jurriaans Suzanne, Bakker Margreet, Parkin Neil T, van der Hoek Lia

Abstract excerpt

OBJECTIVE/DESIGN: To identify new drug-resistance-associated mutations in the HIV-1 reverse transcriptase (RT) protein, we screened the RT sequence database of our hospital for alternative amino acid substitutions at known RT drug-resistance positions. METHOD: The genotypic database used for this analysis contained 1322 RT sequences from 1015 patients. We analysed this RT database with a focus on alternative...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16847406
DOI: 10.1097/01.aids.0000237367.56864.75

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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