Article
Extended spectrum of HIV-1 reverse transcriptase mutations in patients receiving multiple nucleoside analog inhibitors.
AIDS (London, England) - 11 Apr 2003
Gonzales Matthew J, Wu Thomas D, Taylor Jonathan, Belitskaya Ilana, Kantor Rami, Israelski Dennis, Chou Sunwen, Zolopa Andrew R, Fessel W Jeffrey, Shafer Robert W
Abstract excerpt
OBJECTIVE: To characterize reverse transcriptase (RT) mutations by their association with extent of nucleoside RT inhibitor (NRTI) therapy. To identify mutational clusters in RT sequences from persons receiving multiple NRTI. DESIGN: A total of 1210 RT sequences from persons with known antiretroviral therapy were analyzed: 641 new sequences were performed at Stanford University Hospital; 569 were previously...
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