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Article

Factors regulating the abundance and localization of synaptobrevin in the plasma membrane.

Proceedings of the National Academy of Sciences of the United States of America - 25 Jul 2006

Dittman Jeremy S, Kaplan Joshua M

Abstract excerpt

After synaptic vesicle fusion, vesicle proteins must be segregated from plasma membrane proteins and recycled to maintain a functional vesicle pool. We monitored the distribution of synaptobrevin, a vesicle protein required for exocytosis, in Caenorhabditis elegans motor neurons by using a pH-sensitive synaptobrevin GFP fusion protein, synaptopHluorin. We estimated that 30% of synaptobrevin was present in the...

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Identifiers

PMID: 16844789
DOI: 10.1073/pnas.0600784103
PMCID: PMC1544097

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