Article
Rabx-5 regulates RAB-5 early endosomal compartments and synaptic vesicles in C. elegans.
PloS one - 1 Jan 2012
Sann Sharon B, Crane Matthew M, Lu Hang, Jin Yishi
Abstract excerpt
Early endosomal membrane compartments are required for the formation and recycling of synaptic vesicles, but how these compartments are regulated is incompletely understood. We performed a forward genetic screen in C. elegans for mutations that affect RAB-5 labeled early endosomal compartments in GABAergic motoneurons. Here we report the isolation and characterization of one mutation, rabx-5. The rabx-5 mutation...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.