Synaptotagmin controls and modulates synaptic-vesicle fusion in a Ca(2+)-dependent manner.

doi:10.1016/0166-2236(95)93898-8

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Article

Synaptotagmin controls and modulates synaptic-vesicle fusion in a Ca(2+)-dependent manner.

Trends in neurosciences - 1 Apr 1995

Littleton J T, Bellen H J

Abstract excerpt

Although numerous electrophysiological and biochemical studies have defined many of the properties of the putative Ca2+ receptor for exocytosis at the synapse, the molecular mechanisms that couple influx of Ca2+ and release of neurotransmitter have remained elusive. Several proteins have emerged...

Topics

Animals
Biological Evolution
Calcium
Calcium-Binding Proteins
Exocytosis
Humans
Membrane Glycoproteins
Mutation
Nerve Tissue Proteins
Neurotransmitter Agents
Synaptic Vesicles
Synaptotagmins

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