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Article

Structural determinants of synaptobrevin 2 function in synaptic vesicle fusion.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 21 Jun 2006

Deák Ferenc, Shin Ok-Ho, Kavalali Ege T, Südhof Thomas C

Abstract excerpt

Deletion of synaptobrevin/vesicle-associated membrane protein, the major synaptic vesicle soluble N-ethylmaleimide-sensitive factor attachment protein receptor (R-SNARE), severely decreases but does not abolish spontaneous and evoked synaptic vesicle exocytosis. We now show that the closely related R-SNARE protein cellubrevin rescues synaptic transmission in synaptobrevin-deficient neurons but that deletion of...

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Identifiers

PMID: 16793874
DOI: 10.1523/JNEUROSCI.5272-05.2006
PMCID: PMC6673840

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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