Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A complex plasma plant sterol locus on mouse chromosome 14 has at least two genes regulating intestinal sterol absorption.

Journal of lipid research - 1 Oct 2006

Sehayek Ephraim, Fung Yee Yan, Yu Hannah J, Lembcke Jan, Ceglarek Uta, Teupser Daniel, Thiery Joachim, Lutjohann Dieter, von Bergmann Klaus, Breslow Jan L

Abstract excerpt

We previously identified two inbred mouse strains, C57BL/6J and CASA/Rk, with different plasma plant sterol levels. An intercross between these strains revealed a broad plasma plant sterol locus on chromosome 14, which peaked at 17 centimorgan (cM) with a maximum logarithm of the odds score of 9.9. Studies in a chromosome 14 congenic strain, 14KK, with a 4-60 cM CASA/Rk interval on the C57BL/6J background...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Congenic
Share to Chromosome Mapping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Mammalian

Share to Intestinal Absorption

Share to Mice, Inbred C57BL

Share to Phytosterols

Share to Species Specificity

Source

Identifiers

PMID: 16840795
DOI: 10.1194/jlr.M600202-JLR200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A complex plasma plant sterol locus on mouse chromosome 14 has at least two genes regulating intestinal sterol absorption.PMID 16840795Read ↗

Loci on chromosomes 14 and 2, distinct from ABCG5/ABCG8, regulate plasma plant sterol levels in a C57BL/6J x CASA/Rk intercross.Semantic proximity Read ↗

Cathepsin B is a novel gender-dependent determinant of cholesterol absorption from the intestine.Semantic proximity Read ↗

QTL mapping for genetic determinants of lipoprotein cholesterol levels in combined crosses of inbred mouse strains.Semantic proximity Read ↗

Mouse models for genetic dissection of polygenic gastrointestinal diseases.Semantic proximity Read ↗

Genetic factors at the enterocyte level account for variations inintestinal cholesterol absorption efficiency among inbred strains of miceSemantic proximity Read ↗

Impact of diet and genes on murine autoimmune pancreatitis.Semantic proximity Read ↗

New quantitative trait loci that contribute to cholesterol gallstone formation detected in an intercross of CAST/Ei and 129S1/SvImJ inbred mice.Semantic proximity Read ↗

Genetics of responsiveness to high-fat and high-cholesterol diets in the mouse.Semantic proximity Read ↗

Quantitative trait loci that determine lipoprotein cholesterol levels in an intercross of 129S1/SvImJ and CAST/Ei inbred mice.Semantic proximity Read ↗

Two loci on chromosome 9 control bile acid composition: evidence that a strong candidate gene, Cyp8b1, is not the culprit.Semantic proximity Read ↗

Lith6: a new QTL for cholesterol gallstones from an intercross of CAST/Ei and DBA/2J inbred mouse strains.Semantic proximity Read ↗

Two novel quantitative trait loci on mouse chromosomes 6 and 4 independently and synergistically regulate plasma apoB levels.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.