Article
Impact of diet and genes on murine autoimmune pancreatitis.
Journal of cellular and molecular medicine - 1 Aug 2020
Jaster Robert, Gupta Yask, Rohde Sarah, Ehlers Luise, Nizze Horst, Vorobyev Artem, Ludwig Ralf J, Ibrahim Saleh M
Abstract excerpt
The impact of environmental factors, such as diet, and the genetic basis of autoimmune pancreatitis (AIP) are largely unknown. Here, we used an experimental murine AIP model to identify the contribution of diet to AIP development, as well as to fine-map AIP-associated genes in outbred mice prone to develop the disease. For this purpose, we fed mice of an autoimmune-prone intercross line (AIL) three different...
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