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Article

Mouse models for genetic dissection of polygenic gastrointestinal diseases.

European journal of clinical investigation - 1 Feb 2003

Hillebrandt S, Matern S, Lammert F

Abstract excerpt

Many diseases with a major public health impact are the result of complex interactions between environmental factors and multiple genes. In the past decade, methods for genome analysis, in particular quantitative trait locus (QTL) analysis in animal models, were developed to identify and localize the genes responsible for multifactorial (polygenic) diseases; QTL analysis is based on experimental crosses between...

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PMID: 12588290
DOI: 10.1046/j.1365-2362.2003.01089.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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