Article
Tau genotype: no effect on onset, symptom severity, or survival in progressive supranuclear palsy.
Neurology - 10 Jul 2001
Litvan I, Baker M, Hutton M
Abstract excerpt
Genetic studies have shown that progressive supranuclear palsy (PSP) is associated with inheritance of a specific genotype (H1/H1) in the tau gene. The authors investigated whether the H1/H1 genotype or A0/A0 genotype independently or in conjunction with selected environmental risk factors influences the age at onset, severity, or survival in patients with PSP. Our findings suggest that tau genotyping does not...
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