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Article

The prevalence of BRCA1 and BRCA2 mutations in eastern Chinese women with breast cancer.

Journal of cancer research and clinical oncology - 1 Oct 2006

Song Chuan-Gui, Hu Zhen, Wu Jiong, Luo Jian-Min, Shen Zhen-Zhou, Huang Wei, Shao Zhi-Ming

Abstract excerpt

To investigate the prevalence of BRCA1 and BRCA2 mutations among Chinese patients, we studied 70 Shanghai cases with early onset breast cancer and affected relatives, and mutation screening was performed in the whole-gene sequence of BRCA1 and BRCA2 by polymerase chain reaction-based denaturing high-performance liquid chromatography. Six disease-causing mutations in BRCA1 (8.6%) and two in BRCA2 (2.9%) were...

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Source

Identifiers

PMID: 16835750
DOI: 10.1007/s00432-006-0105-9

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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