Article
[Mutational analysis of BRCA1 and BRCA2 genes in early-onset breast cancer patients in Shanghai].
Zhonghua yi xue za zhi - 16 Nov 2005
Song Chuan-gui, Hu Zhen, Yuan Wen-tao, Di Gen-hong, Shen Zhen-zhou, Huang Wei, Shao Zhi-min
Abstract excerpt
OBJECTIVE: To investigate the prevalence of BRCA1 and BRCA2 mutations among early-onset breast cancer patients in Shanghai. METHODS: Fifty patients unselected for family history, who were diagnosed with breast cancer before the age of 40 years were analyzed. Among them, 13 patients have at least one first-degree relative affected with breast cancer. Mutation screening of BRCA1 and BRCA2 was performed in the whole...
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