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Article

BRCA1 and BRCA2 sequence variants in Chinese breast cancer families.

Human mutation - 1 Dec 2002

Zhi Xiangcheng, Szabo Csilla, Chopin Sandrine, Suter Nicola, Wang Qing-Sheng, Ostrander Elaine A, Sinilnikova Olga M, Lenoir Gilbert M, Goldgar David, Shi Yu-Rong

Abstract excerpt

A series of 45 high-risk breast cancer patients, consisting of 25 affected individuals from 16 families in China with at least two cases of breast cancer and 20 cases of breast cancer diagnosed under age 35 without reported family history, were studied for germline mutations of the BRCA1 and BRCA2 genes. Thirteen of the 16 families contained at least one case diagnosed under age 50. Three distinct protein...

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Source

Identifiers

PMID: 12442274
DOI: 10.1002/humu.9083

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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