Article
Prevalence of breast cancer predisposition gene mutations in Chinese women and guidelines for genetic testing.
Clinica chimica acta; international journal of clinical chemistry - 1 Nov 2001
Tang N L, Choy K W, Pang C P, Yeo W, Johnson P J
Abstract excerpt
BACKGROUND: Breast cancer is the most common cancer among Caucasian females. On average, 1 in 12 women will have breast cancer during their lifetime. There is a marked difference in breast cancer incidence in Chinese. In Hong Kong women, the lifetime risk is 1 in 29. BRCA1 and BRCA2 are high-penetrant cancer predisposition genes, but the prevalence and nature of mutations in these genes appear to be...
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