Article
Mechanism of inhibition of Rho-dependent transcription termination by bacteriophage P4 protein Psu.
The Journal of biological chemistry - 8 Sept 2006
Pani Bibhusita, Banerjee Sharmistha, Chalissery Jisha, Muralimohan Abishek, Abishek Muralimohan, Loganathan Ramya Malarini, Suganthan Ragan Babu, Sen Ranjan
Abstract excerpt
Psu, a coat protein from bacteriophage P4, has been shown to inhibit Rho-dependent transcription termination in vivo. Co-overexpression of Psu and Rho led to the loss of viability of the cells, which is the consequence of the anti-Rho activity of the protein. The antitermination property of Psu is abolished either by the deletion of 10 or 20 amino acids from its C terminus or by a mutation, Y80C, in Rho. All...
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