Article
Transcription termination defective mutants of Rho: role of different functions of Rho in releasing RNA from the elongation complex.
Journal of molecular biology - 24 Aug 2007
Chalissery Jisha, Banerjee Sharmistha, Bandey Irfan, Sen Ranjan
Abstract excerpt
The transcription termination factor Rho of Escherichia coli is a RNA binding protein which can translocate along the RNA and unwind the RNA:DNA hybrid using the RNA-dependent ATPase activity. In order to investigate the involvement of each of these functions in releasing RNA from the elongation complex, we have isolated different termination defective mutants of Rho by random mutagenesis, characterized them for...
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