Article
Reduced Rho-dependent transcription termination permits NusA-independent growth of Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America - 2 Aug 1994
Zheng C, Friedman D I
Abstract excerpt
NusA and Rho are essential Escherichia coli proteins that influence transcription elongation and termination. We show that an E. coli derivative unable to express NusA, because its sole nusA gene contains a large deletion/substitution, is viable providing that the bacterium also carries a rho mutation that reduces transcription termination. This Rho-mediated suppression is not allele specific, since either a...
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