Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcription Elongation Factor NusA Is a General Antagonist of Rho-dependent Termination in Escherichia coli.

The Journal of biological chemistry - 8 Apr 2016

Qayyum M Zuhaib, Dey Debashish, Sen Ranjan

Abstract excerpt

NusA is an essential protein that binds to RNA polymerase and also to the nascent RNA and influences transcription by inducing pausing and facilitating the process of transcription termination/antitermination. Its participation in Rho-dependent transcription termination has been perceived, but the molecular nature of this involvement is not known. We hypothesized that, because both Rho and NusA are RNA-binding...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA-Directed RNA Polymerases
Share to Escherichia coli Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Bacterial

Share to Protein Structure, Tertiary

Share to Rho Factor

Share to RNA, Bacterial

Share to rRNA Operon

Share to Transcriptional Elongation Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 26872975
DOI: 10.1074/jbc.M115.701268
PMCID: PMC4825012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcription Elongation Factor NusA Is a General Antagonist of Rho-dependent Termination in Escherichia coli.PMID 26872975Read ↗

Reduced Rho-dependent transcription termination permits NusA-independent growth of Escherichia coli.Semantic proximity Read ↗

The C-terminal domain of the alpha subunit of Escherichia coli RNA polymerase is required for efficient rho-dependent transcription termination.Semantic proximity Read ↗

The antiterminator NusB enhances termination at a sub-optimal Rho site.Semantic proximity Read ↗

NusA modulates intragenic termination by different pathways.Semantic proximity Read ↗

Compromised factor-dependent transcription termination in a nusA mutant of Escherichia coli: spectrum of termination efficiencies generated by perturbations of Rho, NusG, NusA, and H-NS family proteins.Semantic proximity Read ↗

The alpha subunit of E. coli RNA polymerase activates RNA binding by NusA.Semantic proximity Read ↗

Redundancy of primary RNA-binding functions of the bacterial transcription terminator Rho.Semantic proximity Read ↗

Elongation factor NusG interacts with termination factor rho to regulate termination and antitermination of transcription.Semantic proximity Read ↗

New discoveries linking transcription to DNA repair and damage tolerance pathways.Semantic proximity Read ↗

NusA is required for ribosomal antitermination and for modulation of the transcription elongation rate of both antiterminated RNA and mRNA.Semantic proximity Read ↗

In vivo effect of NusB and NusG on rRNA transcription antitermination.Semantic proximity Read ↗

Effect of Escherichia coli nusG function on lambda N-mediated transcription antitermination.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.