Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The C-terminal domain of the alpha subunit of Escherichia coli RNA polymerase is required for efficient rho-dependent transcription termination.

Journal of molecular biology - 18 Dec 1998

Kainz M, Gourse R L

Abstract excerpt

We screened a collection of single alanine residue substitution mutants spanning the entire C-terminal domain of the alpha subunit (alphaCTD) of Escherichia coli RNA polymerase (RNAP) for defects in rho-dependent transcription termination at lambdatR1 in vivo and in vitro, and thereby identified a patch of amino acid residues in the alphaCTD required for efficient rho-dependent termination. NusA addition led to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Escherichia coli
Share to Escherichia coli Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Models, Molecular

Share to Mutation

Share to Recombinant Proteins

Share to Transcription Factors

Share to Transcription, Genetic

Source

Identifiers

PMID: 9878357
DOI: 10.1006/jmbi.1998.2272

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The C-terminal domain of the alpha subunit of Escherichia coli RNA polymerase is required for efficient rho-dependent transcription termination.PMID 9878357Read ↗

Reduced Rho-dependent transcription termination permits NusA-independent growth of Escherichia coli.Semantic proximity Read ↗

Transcription Elongation Factor NusA Is a General Antagonist of Rho-dependent Termination in Escherichia coli.Semantic proximity Read ↗

The alpha subunit of E. coli RNA polymerase activates RNA binding by NusA.Semantic proximity Read ↗

Compromised factor-dependent transcription termination in a nusA mutant of Escherichia coli: spectrum of termination efficiencies generated by perturbations of Rho, NusG, NusA, and H-NS family proteins.Semantic proximity Read ↗

Localization of nusA-suppressing amino acid substitutions in the conserved regions of the beta' subunit of Escherichia coli RNA polymerase.Semantic proximity Read ↗

The antiterminator NusB enhances termination at a sub-optimal Rho site.Semantic proximity Read ↗

NusA modulates intragenic termination by different pathways.Semantic proximity Read ↗

In vitro characterization of transcription termination factor Rho from Escherichia coli rho(nusD) mutants.Semantic proximity Read ↗

Pleiotropic effects of the rpoC10 mutation affecting the RNA polymerase beta' subunit of Escherichia coli on factor-dependent transcription termination and antitermination.Semantic proximity Read ↗

An allosteric mechanism of Rho-dependent transcription termination.Semantic proximity Read ↗

The alpha subunit of RNA polymerase and transcription antitermination.Semantic proximity Read ↗

Elongation factor NusG interacts with termination factor rho to regulate termination and antitermination of transcription.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.