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Article

MTHFR C677T and A1298C gene polymorphisms and hyperhomocysteinemia as risk factors of diabetic nephropathy in type 2 diabetes patients.

Diabetes research and clinical practice - 1 Jan 2007

Mtiraoui Nabil, Ezzidi Intissar, Chaieb Molka, Marmouche Hela, Aouni Zied, Chaieb Arbi, Mahjoub Touhami, Vaxillaire Martine, Almawi Wassim Y

Abstract excerpt

Point mutations in methylenetetrahydrofolate reductase (MTHFR) and hyperhomocysteinemia were implicated in the pathogenesis of diabetic nephropathy (DN) in many ethnic groups. This study addressed the association of C677T and A1298C single nucleotide polymorphisms (SNPs) of MTHFR gene with DN in Tunisian type 2 diabetes (T2DM) patients. Study subjects comprised 93 DN patients, 267 patients with normoalbuminuria,...

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Source

Identifiers

PMID: 16828193
DOI: 10.1016/j.diabres.2006.05.018

Genes

MTHFR

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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