Article
The association between two common mutations C677T and A1298C in human methylenetetrahydrofolate reductase gene and the risk for diabetic nephropathy in type II diabetic patients.
The Journal of nutrition - 1 Oct 2000
Shpichinetsky V, Raz I, Friedlander Y, Goldschmidt N, Wexler I D, Ben-Yehuda A, Friedman G
Abstract excerpt
Mutations of the methylenetetrahydrofolate reductase (MTHFR) gene have been shown to be associated with a predisposition to developing diabetic nephropathy (DN) in specific populations. The frequency of two MTHFR mutations, a recently described mutation in the human MTHFR gene A1298C and C677T, whose association with DN is already known, was determined in an Israeli Jewish population with type 2 diabetes mellitus...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.