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Association between MTHFR C677T polymorphism and diabetic nephropathy in the Chinese population: An updated meta-analysis and review.

Nephrology (Carlton, Vic.) - 1 Jan 2016

Xiong Xuan, Lin Xiao-Kun, Xiao Xiao, Qin Dan-Ping, Zhou Dao-Yuan, Hu Jian-Guang, Liu Yan, Zhong Xiao-Shi

Abstract excerpt

To clarify the effects of MTHFR C677T polymorphism on the risk of diabetic nephropathy (DN) in the Chinese population, an updated meta-analysis was performed. Related studies were identified from PubMed, Springer Link, Ovid and Chinese Databases up to 24 February 2015. A total of 15 studies including 1227 DN cases, 586 healthy controls and 1277 diabetes mellitus (DM) controls were involved in this meta-analysis....

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Identifiers

PMID: 26072975
DOI: 10.1111/nep.12541

Genes

MTHFR

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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