Chromosomal sites for hepatitis B virus integration in human hepatocellular carcinoma.

doi:10.1128/JVI.65.12.6761-6764.1991

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Article

Chromosomal sites for hepatitis B virus integration in human hepatocellular carcinoma.

Journal of virology - 1 Dec 1991

Tokino T, Matsubara K

Abstract excerpt

The discovery that hepatitis B virus (HBV) integrates into host chromosomes raises the question of whether such viral DNA integration correlates directly with the activation of specific oncogenes or the inactivation of anti-oncogenes. To obtain insight into this problem, we randomly collected HBV...

Topics

Alleles
Carcinoma, Hepatocellular
Chromosome Mapping
Chromosomes, Human, Pair 11
Chromosomes, Human, Pair 17
Cosmids
Genetic Linkage
Genotype
Hepatitis B virus
Humans
Liver Neoplasms
Polymorphism, Restriction Fragment Length
Virus Integration

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