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Article

Catalytic inactivation of human phospholipase D2 by a naturally occurring Gly901Asp mutation.

Archives of medical research - 1 Aug 2006

Yamada Yoshiji, Banno Yoshiko, Yoshida Hitoshi, Kikuchi Ryosuke, Akao Yukihiro, Murate Takashi, Nozawa Yoshinori

Abstract excerpt

BACKGROUND: We previously showed that the 1814C-->T (Thr577Ile) polymorphism of the human phospholipase D2 (PLD2) gene is associated with the prevalence of colorectal cancer, with the T allele representing a risk factor for this condition. However, we failed to detect a difference in PLD activity of cell lysates or membrane fractions between cells transfected with cDNAs encoding the Thr577 or Ile577 variants of...

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Source

Identifiers

PMID: 16824927
DOI: 10.1016/j.arcmed.2006.01.006

Genes

PLD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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