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Article

Common sequence variants of lipoprotein lipase: standardized studies of in vitro expression and catalytic function.

Biochimica et biophysica acta - 26 Jul 1996

Zhang H, Henderson H, Gagne S E, Clee S M, Miao L, Liu G, Hayden M R

Abstract excerpt

We have assessed the functional activity of three common sequence variants of human lipoprotein lipase (LPL). Two of these, Asn291Ser and Asp9Asn arise from missense mutations while the third, Ser447Ter, derives from a nonsense mutation, truncating LPL by two residues. As previous in vitro studies have produced conflicting results, we have re-analyzed the catalytic function of these variants using the COS cell...

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Source

Identifiers

PMID: 8695666
DOI: 10.1016/0005-2760(96)00059-8

Genes

LPL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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