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Article

Structure, genomic DNA typing, and kinetic characterization of the D allozyme of placental alkaline phosphatase (PLAP/ALPP).

Human mutation - 1 Mar 2002

Wennberg Charlotte, Kozlenkov Alexey, Di Mauro Sonia, Fröhlander Nils, Beckman Lars, Hoylaerts Marc F, Millán José Luis

Abstract excerpt

The D allozyme of placental alkaline phosphatase (PLAP) displays enzymatic properties at variance with those of the common PLAP allozymes. We have deduced the amino acid sequence of the PLAP D allele by PCR cloning of its gene, ALPP. Two coding substitutions were found in comparison with the cDNA of the common PLAP F allele, i.e., 692C>G and 1352A>G, which translate into a P209R and E429G substitution. A single...

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Identifiers

PMID: 11857742
DOI: 10.1002/humu.10052

Genes

ALPP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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