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Article

Artery/vein specification is governed by opposing phosphatidylinositol-3 kinase and MAP kinase/ERK signaling.

Current biology : CB - 11 Jul 2006

Hong Charles C, Peterson Quinn P, Hong Ji-Young, Peterson Randall T

Abstract excerpt

Angioblasts are multipotent progenitor cells that give rise to arteries or veins . Genetic disruption of the gridlock gene perturbs the artery/vein balance, resulting in generation of insufficient numbers of arterial cells . However, within angioblasts the precise biochemical signals that determine the artery/vein cell-fate decision are poorly understood. We have identified by chemical screening two classes of...

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Source

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Identifiers

PMID: 16824925
DOI: 10.1016/j.cub.2006.05.046
PMCID: PMC1930149

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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