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Article

Arterialization requires the timely suppression of cell growth.

Nature - 1 Jan 2021

Luo Wen, Garcia-Gonzalez Irene, Fernández-Chacón Macarena, Casquero-Garcia Verónica, Sanchez-Muñoz Maria S, Mühleder Severin, Garcia-Ortega Lourdes, Andrade Jorge, Potente Michael, Benedito Rui

Abstract excerpt

The formation of arteries is thought to occur by the induction of a highly conserved arterial genetic programme in a subset of vessels that will later experience an increase in oxygenated blood flow1,2. The initial steps of arterial specification require both the VEGF and Notch signalling pathways3-5. Here, we combine inducible genetic mosaics and transcriptomics to modulate and define the function of these...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Extracellular Signal-Regulated MAP Kinases

Share to Immunoglobulin J Recombination Signal Sequence-Binding Protein

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Source

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Identifiers

PMID: 33299176
DOI: 10.1038/s41586-020-3018-x
PMCID: PMC7116692

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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