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Article

Akt is a mediator of artery specification during zebrafish development.

Development (Cambridge, England) - 1 Sept 2024

Zhou Wenping, Ghersi Joey J, Ristori Emma, Semanchik Nicole, Prendergast Andrew, Zhang Rong, Carneiro Paola, Baldissera Gabriel, Sessa William C, Nicoli Stefania

Abstract excerpt

The dorsal aorta (DA) is the first major blood vessel to develop in the embryonic cardiovascular system. Its formation is governed by a coordinated process involving the migration, specification, and arrangement of angioblasts into arterial and venous lineages, a process conserved across species. Although vascular endothelial growth factor a (VEGF-A) is known to drive DA specification and formation, the kinases...

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Share to Arteries
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endothelial Cells

Share to Proto-Oncogene Proteins c-akt

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Share to Vascular Endothelial Growth Factor A

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Source

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Identifiers

PMID: 39101673
DOI: 10.1242/dev.202727
PMCID: PMC11441982

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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