Article
Hedgehog signaling is essential for endothelial tube formation during vasculogenesis.
Development (Cambridge, England) - 1 Sept 2004
Vokes Steven A, Yatskievych Tatiana A, Heimark Ronald L, McMahon Jill, McMahon Andrew P, Antin Parker B, Krieg Paul A
Abstract excerpt
During embryonic development, the first blood vessels are formed through the aggregation and subsequent assembly of angioblasts (endothelial precursors) into a network of endothelial tubes, a process known as vasculogenesis. These first vessels generally form in mesoderm that is adjacent to endodermal tissue. Although specification of the angioblast lineage is independent of endoderm interactions, a signal from...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.