Article
The -174G/C interleukin-6 polymorphism influences postoperative interleukin-6 levels and postoperative atrial fibrillation. Is atrial fibrillation an inflammatory complication?
Circulation - 9 Sept 2003
Gaudino Mario, Andreotti Felicita, Zamparelli Roberto, Di Castelnuovo Augusto, Nasso Giuseppe, Burzotta Francesco, Iacoviello Licia, Donati Maria Benedetta, Schiavello Rocco, Maseri Attilio, Possati Gianfederico
Abstract excerpt
BACKGROUND: It has been suggested that inflammation can have a role in the development of atrial arrhythmias after cardiac surgery and that a genetic predisposition to develop postoperative complications exists. This study was conceived to verify if a potential genetic modulator of the systemic inflammatory reaction to cardiopulmonary bypass (the -174 G/C polymorphism of the promoter of the Interleukin-6 gene)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.