Article
Genetic polymorphisms and the risk of stroke after cardiac surgery.
Stroke - 1 Sept 2005
Grocott Hilary P, White William D, Morris Richard W, Podgoreanu Mihai V, Mathew Joseph P, Nielsen Dahlia M, Schwinn Debra A, Newman Mark F
Abstract excerpt
BACKGROUND AND PURPOSE: Stroke represents a significant cause of morbidity and mortality after cardiac surgery. Although the risk of stroke varies according to both patient and procedural factors, the impact of genetic variants on stroke risk is not well understood. Therefore, we tested the hypot...
Topics
- Aged
- Alleles
- C-Reactive Protein
- Cardiopulmonary Bypass
- Female
- Genetic Predisposition to Disease
- Genetic Variation
- Humans
- Inflammation
- Interleukin-6
- Male
- Middle Aged
- Models, Genetic
- Multivariate Analysis
- Mutation
- Odds Ratio
- Polymorphism, Genetic
- Polymorphism, Single Nucleotide