Interleukin 6 G-174C polymorphism influences outcome following coronary revascularization surgery.

doi:10.1532/HSF98.20041120

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Article

Interleukin 6 G-174C polymorphism influences outcome following coronary revascularization surgery.

The heart surgery forum - 1 Jan 2005

Bittar Mohamad N, Carey John A, Barnard James, Fildes James E, Pravica Vera, Yonan Nizar, Hutchinson Ian V

Abstract excerpt

BACKGROUND: Levels of the proinflammatory cytokine interleukin 6 (IL-6) increase after surgery. The functional polymorphism in the IL-6 promoter region, G-174C, is associated with an increased risk of coronary heart disease. We investigated the genetic predisposition in IL-6 response to coronary...

Topics

Adenine
Aged
Alleles
Atrial Fibrillation
Blood Loss, Surgical
Coronary Artery Bypass
Coronary Disease
Female
Genetic Predisposition to Disease
Genotype
Guanine
Homozygote

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Incidence

Interleukin-6

Length of Stay

Male

Middle Aged

Source

Open in PubMed

Identifiers

PMID: 16183563
DOI: 10.1532/HSF98.20041120

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-16183563-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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