Article
Platelet gene polymorphisms and cardiac risk assessment in vascular surgical patients.
Anesthesiology - 1 Dec 2004
Faraday Nauder, Martinez Elizabeth A, Scharpf Robert B, Kasch-Semenza Laura, Dorman Todd, Pronovost Peter J, Perler Bruce, Gerstenblith Gary, Bray Paul F, Fleisher Lee A
Abstract excerpt
BACKGROUND: Current perioperative cardiac risk assessment tools use historic and surgical factors to stratify patient risk. Polymorphisms in platelet glycoprotein (GP) IIIa and GPIbalpha are associated with myocardial ischemic risk in nonsurgical settings, but their relation to perioperative ischemia is unclear. The authors hypothesized that platelet genotype would be an independent predictor of postoperative...
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