Article
Is severe progressive liver disease caused by alpha-1-antitrypsin deficiency more common in children or adults?
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society - 1 Jul 2016
Chu Andrew S, Chopra Kapil B, Perlmutter David H
Abstract excerpt
The classical form of alpha-1-antitrypsin deficiency (A1ATD) is known to cause liver disease in children and adults, but there is relatively little information about the risk of severe, progressive liver disease and the need for liver transplantation. To better understand how newly evolving pharmacological, genetic, and cellular therapies may be targeted according to risk for progressive liver disease, we sought...
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