Developmental variation in copper, zinc and metallothionein mRNA in brindled mutant and nutritionally copper deficient mice.

doi:10.1016/0925-4439(91)90036-9

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Article

Developmental variation in copper, zinc and metallothionein mRNA in brindled mutant and nutritionally copper deficient mice.

Biochimica et biophysica acta - 21 Oct 1991

Mercer J F, Stevenson T, Wake S A, Mitropoulos G, Camakaris J, Danks D M

Abstract excerpt

The concentrations of copper, zinc and metallothionein-I (MT-I) mRNA were determined in the liver, kidney and brain of the brindled mutant mouse from birth until the time of death. Despite accumulation of copper in the kidney of the mutant, MT-I mRNA concentrations were normal. There was no difference between the MT-I mRNA in the brain of mutant and normal in the first 10 days of life, but after day 10...

Topics

Animals
Blotting, Northern
Brain
Copper
Female
Gene Expression Regulation
Kidney
Liver
Male
Metal Metabolism, Inborn Errors
Metallothionein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Mice, Mutant Strains

Mutation

RNA, Messenger

Tyrosine Transaminase

Zinc

Source

Open in PubMed

Identifiers

PMID: 1681908
DOI: 10.1016/0925-4439(91)90036-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1681908-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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