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Article

Reduction of copper and metallothionein in toxic milk mice by tetrathiomolybdate, but not deferiprone.

Journal of inorganic biochemistry - 15 Jan 2002

Czachor Jason D, Cherian M George, Koropatnick James

Abstract excerpt

Copper is both essential for life and toxic. Aberrant regulation of copper at the level of intracellular transport has been associated with inherited diseases, including Wilson's disease (WND) in humans. WND results in accumulation of copper and the copper and zinc-binding protein metallothionein (MT) in liver and other tissues, liver degeneration, and neurological dysfunction. The toxic milk (TX) mutation in...

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PMID: 11803042
DOI: 10.1016/s0162-0134(01)00383-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Reduction of copper and metallothionein in toxic milk mice by tetrathiomolybdate, but not deferiprone.PMID 11803042Read ↗

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