Article
A comparison of phenotype and copper distribution in blotchy and brindled mutant mice and in nutritionally copper deficient controls.
Biological trace element research - 1 Apr 1991
Phillips M, Camakaris J, Danks D M
Abstract excerpt
The murine mottled mutants brindled, Mo br, and blotchy, Mo blo, are valuable animal models for the study of mammalian copper metabolism. In this paper, we present data showing that a nutritionally copper deficient suckling mouse, Cu-, with strong phenotypic similarities to the brindled mutant can be produced by feeding genetically normal dams a copper deficient diet (0.1-0.4 ppm Cu2+) from the day of mating....
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