Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Copper deficient rats and mice both develop anemia but only rats have lower plasma and brain iron levels.

Comparative biochemistry and physiology. Toxicology & pharmacology : CBP - 1 Apr 2008

Pyatskowit Joshua W, Prohaska Joseph R

Abstract excerpt

Iron homeostasis depends on adequate dietary copper but the mechanisms are unknown. Mice (Mus musculus) and rat (Rattus norvegicus) offspring were compared to determine the effect of dietary copper deficiency (Cu-) on iron status of plasma, liver, brain and intestine. Holtzman rat and Hsd:ICR (CD-1) outbred albino mouse dams were fed a Cu- diet and drank deionized water or Cu supplemented water. Offspring were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anemia, Iron-Deficiency
Share to Cation Transport Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Copper

Share to Ferroportin

Share to Intestinal Mucosa

Share to Lactation

Share to Mice, Inbred ICR

Source

Open in PubMed Open full text

Identifiers

PMID: 18178529
DOI: 10.1016/j.cbpc.2007.11.008
PMCID: PMC2295218

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Copper deficient rats and mice both develop anemia but only rats have lower plasma and brain iron levels.PMID 18178529Read ↗

Investigation of iron metabolism in mice expressing a mutant Menke's copper transporting ATPase (Atp7a) protein with diminished activity (Brindled; Mo (Br) (/y) ).Semantic proximity Read ↗

Animal Models of Normal and Disturbed Iron and Copper MetabolismSemantic proximity Read ↗

Copper metabolism in metallothionein-null mice fed a high-zinc dietSemantic proximity Read ↗

Identifying a Window of Vulnerability during Fetal Development in a Maternal Iron Restriction ModelSemantic proximity Read ↗

Lessons learned from genetic and nutritional iron deficiencies.Semantic proximity Read ↗

Reduction of copper and metallothionein in toxic milk mice by tetrathiomolybdate, but not deferiprone.Semantic proximity Read ↗

Modeling the dynamics of mouse iron body distribution: hepcidin is necessary but not sufficient.Semantic proximity Read ↗

Genome-linked toxic responses to dietary iron overload.Semantic proximity Read ↗

Of mice and men: genetic determinants of iron status.Semantic proximity Read ↗

Iron deficiency during pregnancy affects postnatal blood pressure in the ratSemantic proximity Read ↗

Regional brain distribution of metallothionein, zinc and copper in toxic milk mutant and transgenic mice.Semantic proximity Read ↗

Loss of divalent metal transporter 1 function promotes brain copper accumulation and increases impulsivity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.