Metallothionein I and II protect against zinc deficiency and zinc toxicity in mice.

Abstract excerpt

Metallothionein (MT)-bound zinc accumulates when animals are exposed to excess zinc and is depleted under conditions of zinc deficiency, suggesting that MT serves as a means of sequestering excess zinc as well as a zinc reservoir that can be utilized when zinc is deficient. To examine the importance of MT for these processes, mice with null alleles of both MT I and MT II genes were created and the zinc...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Body Weight
• Share to Animals, Newborn
• Share to Bone and Bones