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Article

Maternal BRG1 regulates zygotic genome activation in the mouse.

Genes & development - 1 Jul 2006

Bultman Scott J, Gebuhr Thomas C, Pan Hua, Svoboda Petr, Schultz Richard M, Magnuson Terry

Abstract excerpt

Zygotic genome activation (ZGA) is a nuclear reprogramming event that transforms the genome from transcriptional quiescence at fertilization to robust transcriptional activity shortly thereafter. The ensuing gene expression profile in the cleavage-stage embryo establishes totipotency and is required for further development. Although little is known about the molecular basis of ZGA, oocyte-derived mRNAs and...

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Identifiers

PMID: 16818606
DOI: 10.1101/gad.1435106
PMCID: PMC1522071

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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