Article
Mouse ZAR1-like (XM_359149) colocalizes with mRNA processing components and its dominant-negative mutant caused two-cell-stage embryonic arrest.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Feb 2010
Hu Jianjun, Wang Fengchao, Zhu Xiaoquan, Yuan Ye, Ding Mingxiao, Gao Shaorong
Abstract excerpt
Maternal effect genes and encoding proteins are necessary for nuclear reprogramming and zygotic genome activation. However, the mechanisms that mediate these functions are largely unknown. Here we identified XM_359149, a Zar1-like gene that is predominantly expressed in oocytes and zygotes, which we designated Zar1-like (Zar1l). ZAR1L-EGFP formed multiple cytoplasmic foci in late two-cell-stage embryos....
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