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Zygotic Gene Activation and Maternal Factors in Mammals

1 Jan 2007

Abstract excerpt

Zygotic gene activation (ZGA) is the first event of gene expression after fertilization. Following fertilization, ZGA occurs within a short time interval depending on the animal species. Until ZGA, maternal proteins and transcripts stored in oocytes control embryonic development, indicating the importance of maternal factors for development. Somatic cell cloning also proves the potential of oocyte to reprogram...

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PMID: 17827882
DOI: 10.1262/jrd.19029

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